Risk factors for choledocholithiasis in a south Indian population: A case-control study

被引：3

作者：

Chandran A.P. ^{[1
]}

Sivarajan R.R. ^{[1
]}

Srinivas M. ^{[2
]}

Srinivasan V. ^{[2
]}

Venkataraman J. ^{[2
]}

机构：

[1] Department of Medicine, Stanley Medical College, Chennai, 600 001, Old Jail Road, Royapuram

[2] Department of Gastroenterology and Hepatology, Global Hospitals and Health City, Chennai, 600 100, 439, Cheran Nagar, Perumbakkam

来源：

Indian Journal of Gastroenterology | 2013年 / 32卷 / 6期

关键词：

Epidemiology; Gallstones; Sugar; Vegetables;

D O I：

10.1007/s12664-013-0354-x

中图分类号：

学科分类号：

摘要：

Aim: To identify risk factors for common bile duct (CBD) stones in a south Indian population. Methods: Demographic characteristics and diet details were obtained from patients with isolated CBD stones (Gp I) and those with combined CBD and gallstones (Gp II) and age- and sex-matched controls. The risk factors were compared between the two groups. Results: The demographic characteristics were similar between the two groups and matched controls. The significant risk factors for Gp I were infrequent consumption of green vegetable (odds ratio (OR), 2.3; p < 0.05), intake of tea/coffee (OR 3.3; p < 0.01) and less consumption of sugar (p < 0.01). For Gp II, the risk factors were frequent intake (>3 times per week) of spices (OR, 2.8; p < 0.05), fried foods (OR, 2.7; p < 0.05), tamarind (OR, 2.8; p < 0.01), and quantum of oil (p < 0.01) per month. Green vegetables (OR, 8.5; p < 0.00001) and sugar (9.5 + 4.2 vs. 13.8 + 11.2 g; p < 0.00001) were protective. Between the two groups, the risk factors for Gp II were less frequent green vegetable intake (OR: 6.4; p < 0.00001), more frequent spicy food (0-3 times per week) (OR, 7.0; p < 0.05), and higher monthly oil intake (251 + 105 vs. 292 + 89 mL; p < 0.05). Conclusion: CBD stones in both groups were associated with reduced intake of sugar and green vegetables. Our findings need to be validated in larger studies. © 2013 Indian Society of Gastroenterology.

引用

页码：381 / 385

页数：4

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