Glioblastoma in multiple sclerosis: a case report

被引：0

作者：

Giovanni Frisullo

Agata Katia Patanella

Viviana Nociti

Alessandro Cianfoni

Raffaele Iorio

Assunta Bianco

Alessandro Marti

Pietro Attilio Tonali

Anna Paola Batocchi

机构：

[1] Catholic University,Department of Neuroscience, Institute of Neurology

[2] Fondazione Don Gnocchi,Department of Radiology, Neuroradiology Section

[3] MUSC – Medical University of South Carolina,undefined

来源：

Journal of Neuro-Oncology | 2009年 / 94卷

关键词：

Glioblastoma multiforme; Multiple sclerosis; Transcription factors; Differential diagnosis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Cerebral tumor and multiple sclerosis (MS) relapses can show overlapping clinical and magnetic resonance imaging features. In a previous study we observed in relapsing MS patients increased T-bet, pSTAT1, and pSTAT3 expressions in circulating mononuclear cells. During the data analysis we observed that T-bet, pSTAT1, and pSTAT3 expression was not increased in circulating mononuclear cells from a relapsing-remitting (RR)MS patient with recent onset of new neurological signs due to glioblastoma multiforme. In conclusion, our patient represents an exemplary case which suggests that T-bet, pSTAT1, and pSTAT3 expression in peripheral blood mononuclear cells (PBMCs) might be useful to differentiate MS relapses from other noninflammatory diseases.

引用

页码：141 / 144

页数：3

共 45 条

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