Physiological roles of connexins and pannexins in reproductive organs

被引:0
作者
Mark Kibschull
Alexandra Gellhaus
Diane Carette
Dominique Segretain
Georges Pointis
Jerome Gilleron
机构
[1] Mount Sinai Hospital,Lunenfeld
[2] University of Duisburg-Essen,Tanenbaum Research Institute
[3] UMR S1147,Department of Gynecology and Obstetrics
[4] University Paris Descartes,INSERM U 1065
[5] University of Versailles,undefined
[6] University of Nice Sophia-Antipolis,undefined
来源
Cellular and Molecular Life Sciences | 2015年 / 72卷
关键词
Connexin; Pannexin; Testis; Ovary; Function;
D O I
暂无
中图分类号
学科分类号
摘要
Reproductive organs are complex and well-structured tissues essential to perpetuate the species. In mammals, the male and female reproductive organs vary on their organization, morphology and function. Connectivity between cells in such tissues plays pivotal roles in organogenesis and tissue functions through the regulation of cellular proliferation, migration, differentiation and apoptosis. Connexins and pannexins can be seen as major regulators of these physiological processes. In the present review, we assembled several lines of evidence demonstrating that these two families of proteins are essential for male and female reproduction.
引用
收藏
页码:2879 / 2898
页数:19
相关论文
共 991 条
[1]  
Clermont Y(1972)Kinetics of spermatogenesis in mammals: seminiferous epithelium cycle and spermatogonial renewal Physiol Rev 52 198-236
[2]  
Pointis G(2005)Role of connexin-based gap junction channels in testis Trends Endocrinol Metab 16 300-306
[3]  
Segretain D(2010)Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence Can J Physiol Pharmacol 88 399-413
[4]  
Kidder GM(2009)Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour Eur J Obstet Gynecol Reprod Biol 144 S2-S10
[5]  
Vanderhyden BC(1996)Rat uterine myometrium contains the gap junction protein connexin45, which has a differing temporal expression pattern from connexin43 Am J Obstet Gynecol 175 853-858
[6]  
Shynlova O(1992)Studies of connexin 43 and cell-to-cell coupling in cultured human uterine smooth muscle Am J Obstet Gynecol 167 1267-1277
[7]  
Tsui P(1997)Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals Endocrinology 138 5398-5407
[8]  
Jaffer S(2001)Myometrial maturation and labour Ann Med 33 571-578
[9]  
Lye SJ(2006)Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition J Cell Sci 119 1715-1722
[10]  
Albrecht JL(1996)The gap junction communication channel Cell 84 381-388