Reversal of obesity and liver steatosis in mice via inhibition of aryl hydrocarbon receptor and altered gene expression of CYP1B1, PPARα, SCD1, and osteopontin

被引：0
作者：
Itzel Y. Rojas
Benjamin J. Moyer
Carol S. Ringelberg
Craig R. Tomlinson
机构：
[1] Norris Cotton Cancer Center,Department of Molecular & Systems Biology
[2] Geisel School of Medicine at Dartmouth,undefined
[3] Dartmouth Hitchcock Medical Center,undefined
[4] Geisel School of Medicine at Dartmouth,undefined
[5] Dartmouth Hitchcock Medical Center,undefined
[6] Tufts University School of Medicine,undefined
来源：
International Journal of Obesity | 2020年 / 44卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：948 / 963
页数：15
相关论文
共 50 条
  • [21] Role of aryl hydrocarbon receptor polymorphisms on TCDD-mediated CYP1B1 induction and IgM suppression by human B cells
    Kovalova, Natalia
    Manzan, Maria
    Crawford, Robert
    Kaminski, Norbert
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 309 : 15 - 23
  • [22] Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas
    Chang, Jinghua Tsai
    Chang, Han
    Chen, Po-Hung
    Lin, Shong-Ling
    Lin, Pinpin
    [J]. CLINICAL CANCER RESEARCH, 2007, 13 (01) : 38 - 45
  • [23] Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels
    Jacob A.
    Hartz A.M.S.
    Potin S.
    Coumoul X.
    Yousif S.
    Scherrmann J.-M.
    Bauer B.
    Declèves X.
    [J]. Fluids and Barriers of the CNS, 8 (1)
  • [24] The effect of aryl hydrocarbon receptor ligands on the expression of polymerase (DNA directed) kappa (Polκ), polymerase RNA II (DNA directed) polypeptide A (Po1R2a), CYP1B1 and CYP1A1 genes in rat liver
    Brauze, Damian
    Rawluszko, Agnieszka Anna
    [J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2012, 34 (03) : 819 - 825
  • [25] Role of the aryl hydrocarbon receptor and Cyp1b1 in the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Takemoto, K
    Nakajima, M
    Fujiki, Y
    Katoh, M
    Gonzalez, FJ
    Yokoi, T
    [J]. ARCHIVES OF TOXICOLOGY, 2004, 78 (06) : 309 - 315
  • [26] Role of the aryl hydrocarbon receptor and Cyp1b1 in the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Kei Takemoto
    Miki Nakajima
    Yuto Fujiki
    Miki Katoh
    Frank J. Gonzalez
    Tsuyoshi Yokoi
    [J]. Archives of Toxicology, 2004, 78 : 309 - 315
  • [27] Resveratrol Inhibits Dioxin-Induced Expression of Human CYP1A1 and CYP1B1 by Inhibiting Recruitment of the Aryl Hydrocarbon Receptor Complex and RNA Polymerase II to the Regulatory Regions of the Corresponding Genes
    Beedanagari, Sudheer R.
    Bebenek, Ilona
    Bui, Peter
    Hankinson, Oliver
    [J]. TOXICOLOGICAL SCIENCES, 2009, 110 (01) : 61 - 67
  • [28] Differential induction of Cyp1a1, Cyp1b1, Ahd4, and Nmo1 in murine skin tumors and adjacent normal epidermis by ligands of the aryl hydrocarbon receptor
    Reiners, JJ
    Jones, CL
    Hong, N
    Myrand, SP
    [J]. MOLECULAR CARCINOGENESIS, 1998, 21 (02) : 135 - 146
  • [29] Real-time polymerase chain reaction analysis of CYP1B1 gene expression in human liver
    Chang, TKH
    Chen, J
    Pillay, V
    Ho, JY
    Bandiera, SM
    [J]. TOXICOLOGICAL SCIENCES, 2003, 71 (01) : 11 - 19
  • [30] E-cigarette Aerosol Condensate Enhances Metabolism of Benzo(a) pyrene to Genotoxic Products, and Induces CYP1A1 and CYP1B1, Likely by Activation of the Aryl Hydrocarbon Receptor
    Sun, Yuan-Wan
    Kosinska, Wieslawa
    Guttenplan, Joseph B.
    [J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2019, 16 (14)
12345