Does maternal hypoglycemia during screening glucose assessment identify a pregnancy at-risk for adverse perinatal outcome?

被引：14
作者：
Feinberg J.H. [1 ]
Magann E.F. [2 ]
Morrison J.C. [3 ]
Holman J.R. [1 ]
Polizzotto M.J. [1 ]
机构：
[1] Department of Family Practice, Naval Hospital, Camp Pendleton, CA
[2] Department of Obstetrics and Gynecology, Naval Medical Center, Portsmouth, VA
[3] Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS 39216-4505
来源：
Journal of Perinatology | 2005年 / 25卷 / 8期
关键词：
D O I：
10.1038/sj.jp.7211336
中图分类号：
学科分类号：
摘要：
Objective: To determine the perinatal outcome in pregnancies with maternal hypoglycemia following a second trimester oral glucose challenge test (GCT). Study design: Retrospective case-control study of pregnancies undergoing a second trimester 1-hour oral glucose challenge test (GCT). Hypoglycemic pregnancies (<88 mg/dl) were matched with pregnancies with 1-hour glucoses of >88 mg/dl. Antepartum, intrapartum, and neonatal outcomes were assessed. Results: Over 29 months, 334 hypoglycemic singleton pregnancies were matched with 334 controls. A greater number of special/neonatal intensive care unit (SCN/NICU) admissions occurred in the hypoglycemic group (48/334 (14.4%) vs 29/334 (8.7%) in the control group) (p=0.02). The SCN/NICU admission rate remained after controlling for maternal hypertension, smoking, and preterm birth (p=0.037). The development of pregnancy-induced hypertension in women with hypoglycemia 24/334 (7.2%) compared with euglycemic women 13/334 (3.9%, p<0.06) was not significant. Conclusion: Admission to SCN/NICU is increased in pregnant women with hypoglycemia following a GCT. © 2005 Nature Publishing Group. All rights reserved.
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页码：509 / 513
页数：4
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