Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells

被引:0
作者
Hao-hao Zhang
Shan Kuang
Ying Wang
Xiao-xiao Sun
Yuan Gu
Li-hong Hu
Qiang Yu
机构
[1] Shanghai Institute of Materia Medica,Department of Tumor Pharmacology
[2] Chinese Academy of Sciences,undefined
[3] State Key Laboratory of Drug Research,undefined
[4] Shanghai Institute of Materia Medica,undefined
[5] Chinese Academy of Sciences,undefined
来源
Acta Pharmacologica Sinica | 2015年 / 36卷
关键词
apoptosis; tumor cell line; Chinese herbal drugs; neoplasms; STAT3 transcription factors; Janus kinase 2; DTT; signal transduction; bigelovin; interleukin-6; sesquiterpenes;
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中图分类号
学科分类号
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页码:507 / 516
页数:9
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