Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

被引：3
|
作者：
Cheng-Ye Zhan
Di Chen
Jin-Long Luo
Ying-Hua Shi
You-Ping Zhang
机构：
[1] Intensive Care Unit,
[2] Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,undefined
来源：
Molecular Medicine | 2018年 / 24卷
关键词：
microRNA-31; Sepsis; HMOX1; NF-κB/HIF-1α pathway; Intestinal barrier dysfunction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 26 条
  • [1] Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NE-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis
    Zhan, Cheng-Ye
    Chen, Di
    Luo, Jin-Long
    Shi, Ying-Hua
    Zhang, You-Ping
    MOLECULAR MEDICINE, 2018, 24
  • [2] Interferon-γ-Induced Intestinal Epithelial Barrier Dysfunction by NF-κB/HIF-1α Pathway
    Yang, Songwei
    Yu, Min
    Sun, Lihua
    Xiao, Weidong
    Yang, Xuechao
    Sun, Ligang
    Zhang, Chaojun
    Ma, Yuanhang
    Yang, Hanwenbo
    Liu, Yong
    Lu, Dingsong
    Teitelbaum, Daniel H.
    Yang, Hua
    JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2014, 34 (03): : 195 - 203
  • [3] Protective Role of Somatostatin in Sepsis-Induced Intestinal Barrier Dysfunction through Inhibiting the Activation of NF-κB Pathway
    Xu, Xin
    Zhu, Quanli
    Li, Guoliang
    Ma, Junjian
    Pan, Zhijian
    Wu, Wei
    GASTROENTEROLOGY RESEARCH AND PRACTICE, 2020, 2020
  • [4] Amelioration of hypoxia and LPS-induced intestinal epithelial barrier dysfunction by emodin through the suppression of the NF-κB and HIF-1α signaling pathways
    Qi Lei
    Fu Qiang
    Du Chao
    Wu Di
    Zhang Guoqian
    Yuan Bo
    Yan Lina
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, 34 (06) : 1629 - 1639
  • [5] κ-opioid receptor agonists may alleviate intestinal damage in cardiopulmonary bypass rats by inhibiting the NF-κB/HIF-1α pathway
    Zhang, Xiaoyan
    Sun, Yingjie
    Song, Dandan
    Diao, Yugang
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2020, 20 (01) : 325 - 334
  • [6] Deciphering the Protective Role of HIF-1α Downregulation on HIBD through the MALAT1/miR-140-5p/TGFBR1/NF-κB Signaling Pathway
    Zhang, Jiantao
    Han, Jun
    Li, Nan
    Zhou, Wenli
    MOLECULAR NEUROBIOLOGY, 2025, 62 (03) : 3343 - 3360
  • [7] Protection by silibinin against experimental ischemic stroke: Up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression
    Wang, Chaohui
    Wang, Zhihong
    Zhang, Xiangjian
    Zhang, Xiaolin
    Dong, Lipeng
    Xing, Yinxue
    Li, Yanhua
    Liu, Zongjie
    Chen, Linyu
    Qiao, Huimin
    Wang, Lina
    Zhu, Chunhua
    NEUROSCIENCE LETTERS, 2012, 529 (01) : 45 - 50
  • [8] The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition
    Lijing Zhang
    Zhenling Zhang
    Bojia Liu
    Yanling Jin
    Yan Tian
    Yi Xin
    Zhijun Duan
    Molecular Medicine, 2017, 23 : 215 - 224
  • [9] Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
    Hee Jung Kim
    Jae Seok Jeong
    So Ri Kim
    Seung Yong Park
    Han Jung Chae
    Yong Chul Lee
    Scientific Reports, 3
  • [10] Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
    Kim, Hee Jung
    Jeong, Jae Seok
    Kim, So Ri
    Park, Seung Yong
    Chae, Han Jung
    Lee, Yong Chul
    SCIENTIFIC REPORTS, 2013, 3
123