Comparative genomics of yeast species: new insights into their biology

被引：0

作者：

Enrique Herrero

María Angeles de la Torre

Eulogio Valentín

机构：

[1] University of Lleida,Department of Basic Medical Sciences

[2] University of Valencia,Department of Microbiology and Ecology

来源：

International Microbiology | 2003年 / 6卷

关键词：

Hemiascomycetes; Comparative genomics;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The genomes of two hemiascomycetous yeasts (Saccharomyces cerevisiae and Candida albicans) and one archiascomycete (Schizosaccharomyces pombe) have been completely sequenced and the genes have been annotated. In addition, the genomes of 13 more Hemiascomycetes have been partially sequenced. The amount of data thus obtained provides information on the evolutionary relationships between yeast species. In addition, the differential genetic characteristics of the microorganisms explain a number of distinctive biological traits. Gene order conservation is observed between phylogenetically close species and is lost in distantly related species, probably due to rearrangements of short regions of DNA. However, gene function is much more conserved along evolution. Compared to S. cerevisiae and S. pombe, C. albicans has a larger number of specific genes, i.e., genes not found in other organisms, a fact that can account for the biological characteristics of this pathogenic dimorphic yeast which is able to colonize a large variety of environments.

引用

页码：183 / 190

页数：7

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