Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss

被引:0
作者
Babu Singh
Lynne J. Goldberg
机构
[1] Boston University School of Medicine,Department of Dermatology
[2] Boston University School of Medicine,Department of Pathology and Laboratory Medicine
来源
American Journal of Clinical Dermatology | 2016年 / 17卷
关键词
Hair Follicle; Finasteride; Hair Loss; Pyoderma Gangrenosum; Dermal Papilla;
D O I
暂无
中图分类号
学科分类号
摘要
Platelet-rich plasma (PRP) is a solution derived from whole blood that is enriched in the platelet fraction. Platelets serve as a reservoir of growth factors and cytokines. When platelets are activated in vivo, signaling molecules are released into the immediate microenvironment and activate receptors for various pathways. Historically, PRP has been applied to wound beds to promote healing of complex wounds. Over the last decade, it has served as a valuable therapeutic tool in various specialties such as maxillofacial surgery, plastic surgery, orthopedics and sports medicine. Only recently has PRP been utilized for dermatologic purposes, more specifically, for the treatment of male and female pattern hair loss. In this review, we discuss molecular and cellular pathways upregulated by PRP important in hair folliculogenesis, and examine clinical evidence from all previously published studies involving the use of PRP for pattern hair loss.
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页码:359 / 367
页数:8
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共 77 条
[11]  
Ferraro AS(2014)Principles and methods of preparation of platelet-rich plasma: a review and author’s perspective J Cutan Aesthet Surg. 19 42-333
[12]  
Lanti A(2008)Platelet-rich fibrin: evolution of a second-generation platelet concentrate Indian J Dent Res. 5 329-1046
[13]  
Uebel CO(2009)The platelet proteome Curr Opin Hematol 38 1040-162
[14]  
da Silva JB(2012)Autologous platelet-rich plasma: a potential therapeutic tool for promoting hair growth Dermatol Surg 9 159-36
[15]  
Cantarelli D(2015)Efficacy of platelet-rich plasma in treatment of androgenetic alopecia Asian J Transfus Sci. 6 35-110
[16]  
Cayirh M(2015)The effect of platelet-rich plasma in hair regrowth: a randomized placebo-controlled trial Stem Cells Transl Med. 7 107-219
[17]  
Cahskan E(2014)Is there sufficient research data to use platelet-rich plasma in dermatology? Int J Trichol. 7 213-79
[18]  
Acikgoz G(2014)Platelet-rich plasma in androgenic alopecia: myth or an effective tool J Cutan Aesthet Surg. 28 72-1019
[19]  
Conde-Montero E(2014)The effect of autologous activated platelet right plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation Biomed Res Int. 40 1010-224
[20]  
Horcajada-Reales C(2014)Study of platelet-rich plasma injections in the treatment of androgenetic alopecia through an one-year period J Cutan Aesthet Surg. 30 219-412