MicroRNA-mediated species-specific attenuation of influenza A virus

被引：0
|
作者：
Jasmine T Perez
Alissa M Pham
Maria H Lorini
Mark A Chua
John Steel
Benjamin R tenOever
机构：
[1] Microbiology Graduate School Training Program,Department of Microbiology
[2] Mount Sinai School of Medicine,undefined
[3] Mount Sinai School of Medicine,undefined
[4] Global Health and Emerging Pathogens Institute,undefined
[5] Mount Sinai School of Medicine,undefined
来源：
Nature Biotechnology | 2009年 / 27卷
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摘要：
Traditional methods for modifying viruses to produce live attenuated vaccines are being updated with molecularly targeted approaches. Perez et al. attenuate influenza A viruses by introducing miRNA target sites into the coding region of the viral genome.
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页码：572 / 576
页数：4
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