Vascular diseases investigated ex vivo by using Raman, FT-IR and complementary methods

被引：0
作者：
Katarzyna M. Marzec
Anna Rygula
Marlena Gasior-Glogowska
Kamila Kochan
Krzysztof Czamara
Katarzyna Bulat
Kamilla Malek
Agnieszka Kaczor
Malgorzata Baranska
机构：
[1] Jagiellonian University,Jagiellonian Center for Experimental Therapeutics (JCET)
[2] Jagiellonian University,Faculty of Chemistry
来源：
Pharmacological Reports | 2015年 / 67卷
关键词：
Raman spectroscopy; Infrared spectroscopy; Atomic force microscopy; Vascular diseases; Atherosclerosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This work shows the application of vibrational spectroscopy supported by other complementary techniques in analysis of tissues altered by vascular diseases, in particular atherosclerosis. The analysis of atherosclerotic plaque components, as well as label-free imaging of vessels and identification of biochemical markers of endothelial dysfunction are reported. Additionally, the potential of vibrational spectroscopy imaging in following the disease progression (including calcification) and pathological changes in heart valves is described. The presented research shows the effectiveness of techniques used in the biochemical studies of altered tissues and summarizes their capabilities in research on vascular diseases.
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页码：744 / 750
页数：6
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