Angiogenic factors: role in esophageal cancer, a brief review

被引：0

作者：

Kátia Ladeira

Filipa Macedo

Adhemar Longatto-Filho

Sandra F. Martins

机构：

[1] Portuguese Oncology Institute,Life and Health Sciences Research Institute (ICVS), School of Health Sciences

[2] University of Minho,Pathology Department

[3] ICVS/3B’s-PT Government Associate Laboratory,Laboratory of Medical Investigation (LIM) 14, Faculty of Medicine

[4] Portuguese Oncology Institute,Surgery Department, Coloproctology Unit

[5] Molecular Oncology Research Center,undefined

[6] Hospital Braga,undefined

[7] University of Sao Paulo,undefined

[8] Hospital Braga,undefined

来源：

Esophagus | 2018年 / 15卷

关键词：

Esophageal cancer; HGF; Angiopoietin-2; IL-6; VEGF; TGF-B1;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Esophageal cancer has an aggressive behavior with rapid tumor mass growth and frequently poor prognosis; it is known as one of the most fatal types of cancer worldwide. The identification of potential molecular markers that can predict the response to treatment and the prognosis of this cancer has been subject of a vast investigation in the recent years. Among several molecules, various angiogenic factors that are linked to the tumor development, growth, and invasion, such as VEGF, HGF, angiopoietin-2, IL-6, and TGF-B1, were investigated. In this paper, the authors sought to review the role of these angiogenic factors in prognosis and hypothesize how they can be used as a treatment target.

引用

页码：53 / 58

页数：5

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