The synthetic and therapeutic expedition of isoxazole and its analogs

被引:0
作者
Neetu Agrawal
Pradeep Mishra
机构
[1] GLA University,Institute of Pharmaceutical Research
来源
Medicinal Chemistry Research | 2018年 / 27卷
关键词
Heterocyclic; Isoxazole; Biological activity; Anticancer; Anti-inflammatory; Antimicrobial;
D O I
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中图分类号
学科分类号
摘要
Isoxazole, constituting an important family of five-membered heterocycles with one oxygen atom and one nitrogen atom at adjacent positions is of immense importance because of its wide spectrum of biological activities and therapeutic potential. It is, therefore, of prime importance that the development of new synthetic strategies and designing of new isoxazole derivatives should be based on the most recent knowledge emerging from the latest research. This review is an endeavor to highlight the progress in the chemistry and biological activity of isoxazole derivatives which could provide a low-height flying bird’s eye view of isoxazole derivatives to the medicinal chemists for the development of clinically viable drugs using this information.
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页码:1309 / 1344
页数:35
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