Optocapacitance: physical basis and its application

被引:0
作者
Bernardo I. Pinto
Carlos A. Z. Bassetto
Francisco Bezanilla
机构
[1] The University of Chicago,Department of Biochemistry and Molecular Biology
[2] Universidad de Valparaíso,Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias
来源
Biophysical Reviews | 2022年 / 14卷
关键词
Optocapacitance; Membrane capacitance; Remote neuronal stimulation; Nanoparticles; Temperature;
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学科分类号
摘要
The observation that membrane capacitance increases with temperature has led to the development of new methods of neuronal stimulation using light. The optocapacitive effect refers to a light-induced change in capacitance produced by the heating of the membrane through a photothermal effect. This change in capacitance manifests as a current, named optocapacitive current that depolarizes cells and therefore can be used to stimulate excitable tissues. Here, we discuss how optocapacitance arises from basic membrane properties, the characteristics of the optocapacitive current, its use for neuronal stimulation, and the challenges for its application in vivo.
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页码:569 / 577
页数:8
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