Contribution of Hsc70 to barotolerance in the yeast Saccharomyces cerevisiae

被引：0

作者：

Hitoshi Iwahashi

Solomon Nwaka

Kaoru Obuchi

机构：

[1] National Institute of Bioscience and Human Technology,

[2] Higashi 1-1,undefined

[3] Tsukuba,undefined

[4] Ibaraki 305-8566,undefined

[5] Japan,undefined

[6] Human Stress Signal Research Center,undefined

[7] National Institute of Advanced Industrial Science and Technology,undefined

[8] Tsukuba,undefined

[9] Ibaraki,undefined

[10] Japan,undefined

[11] Present address: Institute of Molecular and Cell Biology,undefined

[12] National Institute of Advanced Industrial Science and Technology,undefined

[13] Tsukuba,undefined

[14] Ibaraki,undefined

[15] Japan,undefined

来源：

Extremophiles | 2001年 / 5卷

关键词：

Saccharomyces cerevisiae Barotolerance Thermotolerance Heat-shock protein Molecular chaperone;

D O I：

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中图分类号：

学科分类号：

摘要：

The contribution of Hsc70 to barotolerance in logarithmic-phase cells of the HSC70 (ssb1 and ssb2) deletion mutant and in strains expressing the HSC70 gene on either a low- or a high-copy-number plasmid was studied. The deletion-mutant strain had higher thermotolerance and a slightly lower barotolerance than the control strain. The strain that expresses the HSC70 gene in high copy number had a higher barotolerance than the strain that expresses the gene in low copy number. These results suggest that Hsc70 contributes to barotolerance during exponentially growing conditions as does Hsp104 during heat-shock treatment.

引用

页码：417 / 421

页数：4