Piezo2 is required for Merkel-cell mechanotransduction

被引：0
|
作者：
Seung-Hyun Woo
Sanjeev Ranade
Andy D. Weyer
Adrienne E. Dubin
Yoshichika Baba
Zhaozhu Qiu
Matt Petrus
Takashi Miyamoto
Kritika Reddy
Ellen A. Lumpkin
Cheryl L. Stucky
Ardem Patapoutian
机构：
[1] Howard Hughes Medical Institute,Departments of Cell Biology
[2] Molecular and Cellular Neuroscience,Departments of Dermatology & Physiology and Cellular Biophysics
[3] The Scripps Research Institute,undefined
[4] Neurobiology,undefined
[5] and Anatomy,undefined
[6] Medical College of Wisconsin,undefined
[7] Columbia University,undefined
[8] Genomics Institute of the Novartis Research Foundation,undefined
[9] Present address: Gladstone Institute of Neurological Disease,undefined
[10] San Francisco,undefined
[11] California 94158,undefined
[12] USA.,undefined
来源：
Nature | 2014年 / 509卷
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学科分类号：
摘要：
A mouse study shows that non-neuronal epidermal Merkel cells aid fine-touch perception in the skin through their expression of the Piezo2 mechanosensitive cation channel which then actively tunes the response to touch in adjacent somatosensory neurons.
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页码：622 / 626
页数：4
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