Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors

被引:0
作者
Matthew E. Hardee
Rose J. Eapen
Zahid N. Rabbani
Matthew R. Dreher
Jeffrey Marks
Kimberly L. Blackwell
Mark W. Dewhirst
机构
[1] Duke University Medical Center,Department of Pathology
[2] University of North Carolina Medical Center,Department of Otolaryngology
[3] Duke University Medical Center,Department of Radiation Oncology
[4] National Institutes of Health Clinical Center,Department of Diagnostic Radiology
[5] Duke University Medical Center,Department of Surgery
[6] Duke University Medical Center,Department of Medicine
来源
Cancer Chemotherapy and Pharmacology | 2009年 / 63卷
关键词
Her2/neu; Angiogenesis; Tumor hypoxia; Breast cancer;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:219 / 228
页数:9
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[1]  
Graeber TG(1996)Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 88-91
[2]  
Osmanian C(2004)Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response Oncologist 9 4-9
[3]  
Jacks T(1996)Hypoxic stress proteins: survival of the fittest Semin Radiat Oncol 6 46-58
[4]  
Housman DE(2001)Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis Breast Cancer Res 3 318-322
[5]  
Koch CJ(2000)Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1 J Clin Invest 106 809-812
[6]  
Lowe SW(2000)Oxygen regulation of gene expression: a study in opposites Mol Genet Metab 71 371-380
[7]  
Giaccia AJ(2001)Activation of the HIF pathway in cancer Curr Opin Genet Dev 11 293-299
[8]  
Vaupel P(1998)The unique physiology of solid tumors: opportunities (and problems) for cancer therapy Cancer Res 58 1408-1416
[9]  
Harrison L(1995)Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors Acta Oncol 34 313-316
[10]  
Giaccia AJ(1998)Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels Adv Exp Med Biol 454 629-634