Substrate specificity of guinea pig liver aldehyde oxidase and bovine milk xanthine oxidase for methyl- and nitrobenzaldehydes

被引：0
|
作者：
Aristidis S. Veskoukis
Demetrios Kouretas
Georgios I. Panoutsopoulos
机构：
[1] University of Thessaly,School of Biochemistry and Biotechnology
来源：
European Journal of Drug Metabolism and Pharmacokinetics | 2006年 / 31卷
关键词：
aldehyde oxidase; substituted benzaldehydes; methylbenzaldehyde; nitrobenzaldehyde; xanthine oxidase;
D O I：
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学科分类号：
摘要：
Both aldehyde oxidase and xanthine oxidase catalyze the oxidation of a wide range of N-heterocycles and aldehydes. These enzymes are important in the oxidation of N-heterocyclic xenobiotics, whereas their role in the oxidation of xenobiotic aldehydes is usually ignored. p ]The present investigation describes the interaction of methyl- and nitrosubstituted benzaldehydes, in theortho-,meta- andpara-positions, with guinea pig liver aldehyde oxidase and bovine milk xanthine oxidase.
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页码：11 / 16
页数：5
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