Pauci-immune crescentic glomerulonephritis associated with use of trimethoprim–sulfamethoxazole

被引：0
作者：
Shruti S. Hegde
Vanesa Bijol
Bertrand L. Jaber
机构：
[1] St. Elizabeth’s Medical Center,Division of Nephrology, Department of Medicine
[2] Tufts University School of Medicine,Department of Medicine
[3] Brigham and Women’s Hospital,Department of Pathology
[4] Harvard Medical School,undefined
来源：
CEN Case Reports | 2016年 / 5卷 / 2期
关键词：
Trimethoprim–sulfamethoxazole; Rapidly progressive glomerulonephritis; Pauci-immune crescentic glomerulonephritis;
D O I：
10.1007/s13730-016-0222-5
中图分类号：
学科分类号：
摘要：
Drug-induced pauci-immune crescentic glomerulonephritis has been described with several agents, including propylthiouracil, minocycline, d-penicillamine, and hydralazine. We present the case of a 60-year-old man who presented with rapidly progressive glomerulonephritis in the setting of recent use of trimethoprim–sulfamethoxazole complicated by the development of the Stevens–Johnson syndrome, and was found to have biopsy-proven pauci-immune crescentic glomerulonephritis and undetectable anti-neutrophilic cytoplasmic antibodies. We review the existing literature on the potential association between sulfonamides and hypersensitivity polyangiitis.
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页码：188 / 191
页数：3
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