Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques

被引：0
作者：
Pranav Preman
Julia TCW
Sara Calafate
An Snellinx
Maria Alfonso-Triguero
Nikky Corthout
Sebastian Munck
Dietmar Rudolf Thal
Alison M Goate
Bart De Strooper
Amaia M Arranz
机构：
[1] VIB Center for Brain & Disease Research,Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI)
[2] KU Leuven (University of Leuven),Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology
[3] Icahn School of Medicine at Mount Sinai,Department of Neuroscience & Friedman Brain Institute
[4] Icahn School of Medicine at Mount Sinai,Ronald M. Loeb Center for Alzheimer’s disease
[5] Icahn School of Medicine at Mount Sinai,Department of Neurosciences
[6] Achucarro Basque Center for Neuroscience,Laboratory for Neuropathology, Department of Imaging and Pathology, Leuven Brain Institute (LBI), Department of Pathology
[7] Universidad del País Vasco (UPV/EHU),Dementia Research Institute
[8] VIB Bio Imaging Core,undefined
[9] KU Leuven (University of Leuven),undefined
[10] University Hospital Leuven,undefined
[11] University College London,undefined
[12] Ikerbasque Basque Foundation for Science,undefined
来源：
Molecular Neurodegeneration | / 16卷
关键词：
Human induced pluripotent stem cells (hiPSCs); Astrocytes; Chimeric mouse models; Alzheimer’s disease; Amyloid plaques; Apolipoprotein E (; );
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