Neuropsychiatric aspects of pediatric thyrotoxicosis

被引:7
作者
Bhatara V.S. [1 ]
Sankar R. [1 ,2 ]
机构
[1] Department of Thyroidology, Inst. of Nucl. Med. and All. Sci., Timarpur, New Delhi, Lucknow Road
[2] Department of Endocrinology, Thyroid Research Centre, Inst. of Nucl. Med. and All. Sci., Timarpur, New Delhi - 110 054, Lucknow Road
关键词
Dysphoria; Neuropsychiatric changes; Thyrotoxicosis;
D O I
10.1007/BF02761219
中图分类号
学科分类号
摘要
The neurobehavioural and neuropsychiatric changes associated with thyrotoxicosis are multiple and varied. This association is well recognised although the true incidence of neuropsychiatric symptoms in thyrotoxicosis is not known. Review of available literature suggests that frank psychiatric symptoms in thyrotoxicosis may be in the order of 10%. In pediatric thyrotoxicosis the neuropsychiatric symptoms may be pronounced and may antedate the medical diagnosis by six months to one year. One of the classic presentation is deterioration in school performance. Frequently noticed cognitive and behavioural abnormalities in pediatric thyrotoxicosis are hyperactivity, irritability or anxious dysphoria, and problems of attention. Successful treatment of thyrotoxicosis usually leads to resolution of the major mental disturbances associated with it and delayed treatment possibly results in enduring neuropsychiatric problems. Awareness of neuropsychiatric symptomatology can help in early detection and appropriate management of children with thyrotoxicosis.
引用
收藏
页码:277 / 284
页数:7
相关论文
共 42 条
[1]  
Graves R.J., Newly observed affection of the thyroid gland in the females, London Med Surg J, 7, pp. 516-525, (1835)
[2]  
Parry C.H., Collections from the Unpublished Writings of the Late CH Parry, 2, (1825)
[3]  
Saxena K.M., Crawford J.D., Talbot N.B., Childhood thyrotoxicosis : A long-term perspective, Br Med J, 2, pp. 1153-1158, (1964)
[4]  
Barnes H., Blizzard R.M., Antithyroid drug therapy for toxic diffuse goiter (Grave's disease) : Thirty year experience in children and adolescents, J Pediatr, 91, pp. 313-320, (1977)
[5]  
Bhatara V., McMillan M.J., Kummer M., Fire setting and aggressive behaviour in a four year old boy associated with ingestion of ground beef contaminated with bovine thyroid tissue : A case report and review of neuropsychiatric findings in pediatric thyrotoxicosis, J Child Adoles Psychopharmacol, 5, pp. 255-271, (1995)
[6]  
Bhatara V., McMillan M.J., Behavioural and cognitve abnormalities associated with pediatric throtoxicosis, Thyroid Disease of Infancy and Childhood : Effects on Behavioural and Intellectual Development
[7]  
Bhatara V., McMilan M.J., Terv R., Bandettini F., Learning disorders and the thyroid, J Am Child Adolesce Psychia, 35, (1996)
[8]  
Vanderpump M.P.J., Turnbridge W.M.G., The epidemiology of thyroid disease, Werner and Ingbar's The Thyroid : A Fundamental and Clinical Text. Seventh Edition, pp. 474-482, (1996)
[9]  
Stern R.A., Prange A.J., Neuropsychiatric aspects of endocrine disorders, Comprehensive Text Book of Psychiatry VI, Vol 1. 6th Edition, 1, pp. 241-245, (1995)
[10]  
Stern R.A., Robinson B., Thorner A.R., Arruda J.E., Prohaska M.L., Prange A.J., A survey study of neuropsychiatric complaints in patients with Graves' disease, J Neuropsychiatr Clin Neurosci, 8, pp. 181-185, (1996)