How Phospholipid-Cholesterol Interactions Modulate Lipid Lateral Diffusion, as Revealed by Fluorescence Correlation Spectroscopy

被引：0
|
作者：
Nicoletta Kahya
Petra Schwille
机构：
[1] Dresden University of Technology,Institute of Biophysics, Biotechnology Center
[2] Philips Research Laboratories,undefined
来源：
Journal of Fluorescence | 2006年 / 16卷
关键词：
FCS; Confocal fluorescence microscopy; Giant unilamellar vesicles; Lipid-sterol interaction; Cholesterol; Glycerophospholipid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cholesterol is a key player in regulating physico-chemical properties of cellular membranes and, thereby, ensuring cell viability. In particular, lipid-cholesterol interactions may provide important information on the spatio-temporal organization of membrane components. Here, we apply confocal imaging and Fluorescence Correlation Spectroscopy (FCS) to Giant Unilamellar Vesicles (GUVs) composed of binary mixtures of lipids and cholesterol.
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页码：671 / 678
页数：7
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