Nek2B activates the wnt pathway and promotes triple-negative breast cancer chemothezrapy-resistance by stabilizing β-catenin

被引:0
作者
Honghong Shen
Wenpeng Yan
Jinyang Yuan
Ziyue Wang
Chen Wang
机构
[1] Shanxi Medical University,Department of pathology, The Second Clinical Medical College
[2] Shanxi Medical University,Department of general surgery, The Second Clinical Medical College
来源
Journal of Experimental & Clinical Cancer Research | / 38卷
关键词
Nek2B; β-Catenin; Wnt signaling pathway; Triple-negative breast cancer; Chemotherapy resistance;
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[1]  
He Y(2018)Classification of triple-negative breast cancers based on Immunogenomic profiling J Exp Clin Cancer Res 37 327-243
[2]  
Jiang Z(2018)The epigenetics of triple-negative and basal-like breast Cancer: current knowledge J Breast Cancer 21 233-1826
[3]  
Chen C(2018)Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancercells with DNA methyltransferase and histone deacetylase inhibitors J Exp Clin Cancer Res 37 314-907
[4]  
Wang X(2018)Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy Nat Commun 9 3267-847
[5]  
Temian DC(2000)Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos EMBO J 19 1816-365
[6]  
Pop LA(2016)Targeting NEK2 as a promising therapeutic approach for cancer treatment Cell Cycle 15 895-1803
[7]  
Irimie AI(2015)Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer BMC Urol 15 90-1894
[8]  
Berindan-Neagoe I(2013)Nek2-targeted ASO or siRNA pretreatment enhances anticancer drug sensitivity in triple-negative breast cancer cells Int J Oncol 42 839-105
[9]  
Su Y(2014)Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance Front Biosci (Landmark Ed) 19 352-991
[10]  
Hopfinger NR(2017)Ixazomib enhances parathyroid hormone–induced β-catenin/T-cell factor signaling by dissociating β-catenin from the parathyroid hormone receptor Mol Biol Cell 28 1792-147