Diagnostics and management of herpes zoster ophthalmicus

被引:0
作者
Werner R.N. [1 ,2 ]
Steinhorst N.-I. [3 ]
Nast A. [1 ]
Pleyer U. [3 ]
机构
[1] Klinik für Dermatologie, Venerologie und Allergologie, Division of Evidence based Medicine (dEBM), Charité – Universitätsmedizin Berlin, Berlin
[2] MVZ Ärztezentrum Nollendorfplatz, Berlin
[3] Universitäts-Augenklinik, Uveitis Zentrum, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, Berlin
关键词
Acute retinal necrosis syndrome; Anterior uveitis; Complications; Guidelines; Shingles;
D O I
10.1007/s00717-018-0408-7
中图分类号
学科分类号
摘要
Herpes zoster (HZ, shingles) represents the secondary manifestation of an infection with varicellazoster virus (VZV). A reactivation of dormant VZV in the ophthalmic branch of the fifth cranial nerve leads to ophthalmic HZ (HZO). The predominantly older and immune compromised patients often present with eye involvement (approximately 50%) as well as characteristic skin changes. Clinical manifestations include the cornea and conjunctiva but anterior uveitis and (rarely) acute retinal necrosis may also occur. Associated sensory symptoms that range from paresthesia to severe pain may severely affect the quality of life. Particularly in immunocompromised and/or elderly patients, HZO is associated with complicated courses. Systemic antiviral treatment and an adequate pain medication are the mainstay of the recommended management. The present article provides an overview of the contents of the current consensus-based European guidelines on the management of HZ with a specific focus on HZO. © 2018, Springer-Verlag GmbH Austria, ein Teil von Springer Nature.
引用
收藏
页码:201 / 214
页数:13
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