Non-compacted cardiomyopathy: Clinical-echocardiographic study

被引：50
作者：
Espinola-Zavaleta N. [1 ]
Soto M.E. [1 ]
Castellanos L.M. [1 ]
Játiva-Chávez S. [1 ]
Keirns C. [1 ]
机构：
[1] Echocardiography in Outpatient Clinic, Instituto Nacional de Cardiología Ignacio Chávez, Tlalpan, 14080 México, D.F., J. Badiano No.1, Colonia Seccion XVI
来源：
Cardiovascular Ultrasound | / 4卷 / 1期
关键词：
Ventricular Arrhythmia; Functional Class; Premature Ventricular Contraction; Sustained Ventricular Tachycardia; Maximal Wall Thickness;
D O I：
10.1186/1476-7120-4-35
中图分类号：
学科分类号：
摘要：
The aim of the present study was to describe the clinical and echocardiographic findings of ventricular noncompaction in adult patients. Fifty-three patients underwent complete clinical history, electrocardiogram, Holter and transthoracic echocardiogram. Forty patients (75%) were in class I/II of the New York Heart Association, and 13 (25%) in class III/IV. Ventricular and supraventricular escape beats were found in 40% and 26.4%, respectively. Holter showed premature ventricular contractions in 32% and sustained ventricular tachycardia in 7.5%. Ventricular noncompaction was an isolated finding in 74% of cases and was associated with other congenital heart disease in 26%. Noncompacted ventricular myocardium involved only left ventricle in 62% of the patients and both ventricles in 38%. The mean ratio of noncompacted to compacted myocardial layers at the site of maximal wall thickness was 3.4 ± 0.87 mm (range 2.2-7.5). The presence of ventricular noncompaction in more than three segments was associated with a functional class greater than II and ventricular arrhythmia with demonstrable statistical significance by χ2(p < 0.003). Conclusion: a) Noncompacted cardiomyopathy is a congenital pathological entity that can occur in isolated form or associated with other heart disease and often involves both ventricles. b) A ratio of noncompacted to compacted myocardium greater than 3 and involvement of three or more segments are indicators of poor prognosis. c) Since the clinical manifestations are not sufficient to establish diagnosis, echocardiography is the diagnostic tool that makes it possible to document ventricular noncompaction and establish prognostic factors. © 2006 Espinola-Zavaleta et al; licensee BioMed Central Ltd.
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