The mechanism of transglutaminase 2 inhibition with glucosamine: implications of a possible anti-inflammatory effect through transglutaminase inhibition

Begg GE(2006)Mechanism of allosteric regulation of transglutaminase 2 by GTP Proc Natl Acad Sci USA 103 19683-19688

Carrington L(2006)Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity J Biol Chem 281 12603-12609

Stokes PH(1970)Inhibitory effects of D-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis Cancer Res 30 2905-2912

Matthews JM(1971)Inhibition of protein, glycoprotein, ribonucleic acid and deoxyribonucleic acid synthesis by D-glucosamine and other sugars in mouse leukemic cells L5178Y and selective inhibition in SV-3T3 compared with 3T3 cells Biochim Biophys Acta 240 74-93

Wouters MA(1972)Antineoplastic drug activity in the mitotic cycle—effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells Biochem Pharmacol 21 1977-1988

Husain A(2007)Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor Biochemistry 46 1106-1115

Lorand L(2005)Development of a mechanism-based assay for tissue transglutaminase—results of a high-throughput screen and discovery of inhibitors Anal Biochem 338 237-244

Iismaa SE(2006)Glucosamine sulfate inhibits TNF-alpha and IFN-gamma-induced production of ICAM-1 in human retinal pigment epithelial cells in vitro Invest Ophthalmol Vis Sci 47 664-672

Graham RM(2005)Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2 Chem Biol 12 469-475

Begg GE(2006)Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis Biochemistry 45 13163-13174

Begg GE(2006)Mechanism of allosteric regulation of transglutaminase 2 by GTP Proc Natl Acad Sci USA 103 19683-19688

Carrington L(2006)Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity J Biol Chem 281 12603-12609

Stokes PH(1970)Inhibitory effects of D-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis Cancer Res 30 2905-2912

Matthews JM(1971)Inhibition of protein, glycoprotein, ribonucleic acid and deoxyribonucleic acid synthesis by D-glucosamine and other sugars in mouse leukemic cells L5178Y and selective inhibition in SV-3T3 compared with 3T3 cells Biochim Biophys Acta 240 74-93

Wouters MA(1972)Antineoplastic drug activity in the mitotic cycle—effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells Biochem Pharmacol 21 1977-1988

Husain A(2007)Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor Biochemistry 46 1106-1115

Lorand L(2005)Development of a mechanism-based assay for tissue transglutaminase—results of a high-throughput screen and discovery of inhibitors Anal Biochem 338 237-244

Iismaa SE(2006)Glucosamine sulfate inhibits TNF-alpha and IFN-gamma-induced production of ICAM-1 in human retinal pigment epithelial cells in vitro Invest Ophthalmol Vis Sci 47 664-672

Graham RM(2005)Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2 Chem Biol 12 469-475

Begg GE(2006)Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis Biochemistry 45 13163-13174