The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

被引：0
|
作者：
Mouna Guerfal
Stefan Ryckaert
Pieter P Jacobs
Paul Ameloot
Kathleen Van Craenenbroeck
Riet Derycke
Nico Callewaert
机构：
[1] Ghent University,Department of Biochemistry and Microbiology
[2] VIB,Department for Molecular Biomedical Research
[3] Ghent University,Department of Biomedical Molecular Biology
[4] Harvard Medical School,Department of Dermatology, Brigham and Women's Hospital
[5] Oxyrane Belgium,Department of Physiology
[6] Ghent University,undefined
来源：
Microbial Cell Factories | / 9卷
关键词：
Unfold Protein Response; Pichia; Heterologous Protein; AOX1 Promoter; Pastoris GS115 Strain;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins
    Guerfal, Mouna
    Ryckaert, Stefan
    Jacobs, Pieter P.
    Ameloot, Paul
    Van Craenenbroeck, Kathleen
    Derycke, Riet
    Callewaert, Nico
    MICROBIAL CELL FACTORIES, 2010, 9
  • [2] Overexpression of HAC1 gene increased levels of both intracellular and secreted human kringle fragment in Saccharomyces cerevisiae
    Lee, Tae-Hee
    Bae, Yi-Hyun
    Kim, Myoung-Dong
    Seo, Jin-Ho
    PROCESS BIOCHEMISTRY, 2012, 47 (12) : 2300 - 2305
  • [3] Effect of Disruption of Pichia pastoris YPS1 Gene on Viability and Production of Recombinant Proteins
    Sazonova, E. A.
    Zobnina, A. E.
    Padkina, M. V.
    RUSSIAN JOURNAL OF GENETICS, 2013, 49 (06) : 602 - 608
  • [4] Effect of disruption of Pichia pastoris YPS1 gene on viability and production of recombinant proteins
    E. A. Sazonova
    A. E. Zobnina
    M. V. Padkina
    Russian Journal of Genetics, 2013, 49 : 602 - 608
  • [5] Production of Δ1-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris
    Taura, Futoshi
    Dono, Emi
    Sirikantaramas, Supaart
    Yoshimura, Kohji
    Shoyama, Yukihiro
    Morimoto, Satoshi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 361 (03) : 675 - 680
  • [6] Overexpression, purification, and characterization of recombinant barley alpha-amylases 1 and 2 secreted by the methylotrophic yeast Pichia pastoris
    Juge, N
    Andersen, JS
    Tull, D
    Roepstorff, P
    Svensson, B
    PROTEIN EXPRESSION AND PURIFICATION, 1996, 8 (02) : 204 - 214
  • [7] Cloning and characterization of the inulinase gene from a marine yeast Pichia guilliermondii and its expression in Pichia pastoris
    Tong Zhang
    Fang Gong
    Zhe Chi
    Guanglei Liu
    Zhenming Chi
    Jun Sheng
    Jing Li
    Xianghong Wang
    Antonie van Leeuwenhoek, 2009, 95 : 13 - 22
  • [8] Cloning and characterization of the inulinase gene from a marine yeast Pichia guilliermondii and its expression in Pichia pastoris
    Zhang, Tong
    Gong, Fang
    Chi, Zhe
    Liu, Guanglei
    Chi, Zhenming
    Sheng, Jun
    Li, Jing
    Wang, Xianghong
    ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 2009, 95 (01): : 13 - 22
  • [9] High-level production of glucose oxidase in Pichia pastoris: Effects of Hac1p overexpression on cell physiology and enzyme expression
    Yu, Sijie
    Miao, Liangtian
    Huang, He
    Li, Yin
    Zhu, Taicheng
    ENZYME AND MICROBIAL TECHNOLOGY, 2020, 141 (141)
  • [10] Redox Engineering by Ectopic Overexpression of NADH Kinase in Recombinant Pichia pastoris (Komagataella phaffii): Impact on Cell Physiology and Recombinant Production of Secreted Proteins
    Tomas-Gamisans, Marius
    Paim Andrade, Cristiane Conte
    Maresca, Francisco
    Monforte, Sergi
    Ferrer, Pau
    Albiol, Joan
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2020, 86 (06)
12345