Spatiotemporal control of gene expression by a light-switchable transgene system

被引：0
|
作者：
Xue Wang
Xianjun Chen
Yi Yang
机构：
[1] Synthetic Biology and Biotechnology Laboratory,
[2] State Key Laboratory of Bioreactor Engineering,undefined
[3] School of Pharmacy,undefined
[4] East China University of Science and Technology,undefined
来源：
Nature Methods | 2012年 / 9卷 / 3期
关键词：
D O I：
10.1038/nmeth.1892
中图分类号：
学科分类号：
摘要：
A light-inducible dimerization domain is used to create a genetically encoded, light-switchable transactivator of gene expression. The system allows rapid blue light–mediated activation of transgenes containing an appropriate activation sequence with low background and high induction.
引用
收藏
页码：266 / 269
页数：3
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