Tissue microarrays: applications in urological cancer research

被引：0
|
作者：
A. S. Merseburger
A. G. Anastasiadis
J. Hennenlotter
D. Schilling
P. Simon
S. A. Machtens
J. Serth
A. Stenzl
M. A. Kuczyk
机构：
[1] Eberhard Karls University,Department of Urology
[2] Medical Clinic Eberhard Karls University,Department of Sports Medicine
[3] Hannover Medical School,Department of Urology
来源：
World Journal of Urology | 2006年 / 24卷
关键词：
Tissue microarray; TMA; Carcinogenesis; Prostate cancer; Prognosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.
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页码：579 / 584
页数：5
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