In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines

被引:0
作者
Carlos G Leon
Jinkyung Lee
Karen Bartlett
Pavel Gershkovich
Ellen K Wasan
Jinying Zhao
John G Clement
Kishor M Wasan
机构
[1] The University of British Columbia,Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences
[2] The University of British Columbia,Faculty of Environmental and Occupational Health
[3] British Columbia Institute of Technology,School of Health Sciences
[4] iCo Therapeutics Inc.,undefined
来源
Lipids in Health and Disease | / 10卷
关键词
Amphotericin B; Candida; cytotoxicity; monocytes.;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 139 条
[1]  
Calugi C(2011)Novel small molecules for the treatment of infections caused by Candida albicans: a patent review 2 Expert Opin Ther Pat 21 381-97
[2]  
Trabocchi A(2010)Fungal infections in oncology patients: update on epidemiology, prevention, and treatment Curr Opin Oncol 22 138-42
[3]  
Guarna A(2008)Bloodstream infections: evolution and trends in the microbiology workload, incidence, and etiology, 1985-2006 Medicine (Baltimore) 87 234-49
[4]  
Marr KA(2010)Antifungal drug resistance of oral fungi Odontology 98 15-25
[5]  
Rodriguez-Creixems M(1955)A new antifungal antibiotic, amphotericin B Antibiot Annu 3 566-73
[6]  
Alcala L(2005)Molecular modelling of membrane activity of amphotericin B, a polyene macrolide antifungal antibiotic Acta Biochim Pol 52 655-8
[7]  
Munoz P(2011)Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst Microbes Infect 13 457-67
[8]  
Cercenado E(2002)Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance J Hosp Infect 50 243-60
[9]  
Vicente T(1997)Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol delta5,6-desaturation FEBS Lett 400 80-2
[10]  
Bouza E(2004)Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans J Antimicrob Chemother 54 376-85