Morphofunctional Characteristics of Fetoplacental Barrier of Placental Villi during Pregnancy Complicated by Herpes-Virus Infection

被引:0
作者
M. T. Lutsenko
I. A. Andrievskaya
机构
[1] Siberian Division of the Russian Academy of Medical Sciences,Far
来源
Bulletin of Experimental Biology and Medicine | 2010年 / 149卷
关键词
herpes; syncytiotrophoblast; Bcl-2 protein; caspase-3;
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学科分类号
摘要
Analysis of placenta homogenate from pregnant women having an episode of herpes-virus infection during the third trimester revealed suppression of Bcl-2 protein activity and increase in caspase 3 concentration. Activity of Bcl-2 protein decreases with increasing the titer of antibodies to herpes virus. Increased caspase-3 activity increases the risk of DNA damage in syncytiotrophoblast nuclei.
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页码:537 / 539
页数:2
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