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Renal complications in coronavirus disease 2019: a systematic review
被引:0
作者:
Taichiro Minami
Yasunori Iwata
Takashi Wada
机构:
[1] Brigham and Women’s Hospital,Renal Division, Department of Medicine
[2] Kanazawa University,Department of Nephrology and Laboratory Medicine
来源:
Inflammation and Regeneration
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40卷
关键词:
COVID-19;
Renal complication;
AKI;
D O I:
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学科分类号:
摘要:
The world today is facing a pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which mainly causes a respiratory disease known as coronavirus disease 2019 (COVID-19). Therefore, its pathogenesis and complications should be identified and understood. SARS-CoV-2 infects the host using the angiotensin-converting enzyme 2 (ACE2) as its receptor, which is expressed in several organs including the lungs, heart, kidneys, and intestines. Kidney complications are relatively common, and acute kidney injury (AKI) is a life-threatening complication in patients with COVID-19. In this review, the renal histological patterns of COVID-19 are described in detail, and its potential mechanisms associated with AKI are discussed.
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