Silver Nanoparticle Embedded α-Chitin Nanocomposite for Enhanced Antimicrobial and Mosquito Larvicidal Activity

被引:0
作者
Dhananasekaran Solairaj
Palanivel Rameshthangam
机构
[1] Alagappa University,Department of Biotechnology, Science Campus
来源
Journal of Polymers and the Environment | 2017年 / 25卷
关键词
Antimicrobial; α-Chitin/silver nanocomposites; Larvicidal;
D O I
暂无
中图分类号
学科分类号
摘要
Advent of nanotechnology opens up potential avenues for overcoming various challenges that includes control and cure of infectious diseases. The present study is focused on the synthesis of α-chitin nanoparticles (CNP) from the shells of Penaeus monodon Fabricius, silver nanoparticles (AgNP) and α-chitin/silver nanocomposite (CNP/AgNP), and to evaluate their antimicrobial and mosquito larvicidal activities. The antibacterial and antifungal activities are assessed against five different bacterial and fungal strains. Also the mosquito larvicidal potential is studied against Aedes aegypti a potential vector for malaria and dengue fever. The synthesized nanocomposites are characterized using UV–Vis spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscope, energy-dispersive X-ray spectroscopy, transmission electron microscope and dynamic light scattering analysis. The antibacterial and antifungal assays reveal that the CNP/AgNP has an enhanced antimicrobial effect on inhibition of bacteria (P. vulgaris, K. pneumonia and S. aureus) as well as fungi (C. albicans, T. viridae, A. niger and A. alternate). Mosquito larvicidal assays confirm that CNP/AgNP has shown lowest LC50 and LC90 values than CNP and AgNP against all the instars of A. aegypti. Hence our result suggests that the incorporation of AgNP with CNP could improve the antimicrobial and mosquito larvicidal activity and have the potential to be used as biocompatible antimicrobial and mosquito larvicidal material.
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页码:435 / 452
页数:17
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