Atypical genesis of anterior ischemic optic neuropathy

被引：0
作者：
Dutescu, R. M. [1 ,2 ]
Klein, J. P. [1 ]
Schroeter, J. [3 ]
机构：
[1] Charite, Augenklin, Campus Virchow Klinikum, D-13353 Berlin, Germany
[2] RWTH Univ Klinikum Aachen, Klin Augenheilkunde, D-52074 Aachen, Germany
[3] Charite, Inst Transfusionmed, Univ Gewebebank, D-13353 Berlin, Germany
来源：
OPHTHALMOLOGE | 2015年 / 112卷 / 03期
关键词：
Granulomatosis with polyangiitis; Vasculitis; ANCA; Vision loss; Inflammation; WEGENERS-GRANULOMATOSIS; DIAGNOSIS;
D O I：
10.1007/s00347-014-3104-2
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
This article presents a case of arteritic anterior ischemic optic neuropathy as a manifestation of granulomatosis with polyangiitis (GPA). A 52-year-old woman suffered acute unilateral vision loss. Besides a unilateral papillary edema, serological investigations revealed elevated inflammation parameters with a positive (cytoplasmic) anti-neutrophil cytoplasmic autoantibodies (c-ANCA) titer. In addition to the occurrence of pulmonary nodules and cavitary lesions this is indicative for the diagnosis of GPA. Treatment with cyclophosphamide and prednisolone led to a rapid regression of inflammation parameters but no visual improvement occurred.
引用
收藏
页码：272 / 275
页数：4
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