In Vitro Antimicrobial Activity of Telavancin against Methicillin-resistant Staphylococcus aureus Clinical Isolates from Japan (2006)

被引：0
作者：
Kazuo Hatano
Kaoru Matsuzaki
Yumie Sato
Intetsu Kobayashi
Keizo Yamaguchi
机构：
[1] Pharmacology Research Laboratories,Department of Infectious Diseases
[2] Astellas Pharma Inc.,Chemotherapy Division
[3] Mitsubishi Chemical Medience Corporation,Department of Infectious Diseases
[4] Toho University School of Medicine,undefined
来源：
The Journal of Antibiotics | 2007年 / 60卷
关键词：
telavancin; MRSA; surveillance; vancomycin; Japan; lipoglycopeptide;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In vitro antimicrobial activity of telavancin, a rapidly bactericidal lipoglycopeptide, was evaluated against 1500 strains of MRSA recently isolated in Japan. Telavancin had potent activity, with MIC values that ranged from 0.12 μg/ml to 0.5 μg/ml and a MIC90 value of 0.5 μg/ml. The MIC90s of vancomycin and linezolid were 1.0μg/ml and 2 μg/ml, respectively. No vancomycin intermediate resistant or vancomycin-resistant MRSAs were detected in this surveillance study.
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页码：709 / 712
页数：3
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