The effects of female age on the outcome of testicular sperm extraction and intracytoplasmic sperm injection in infertile patients with azoospermia

被引：4
作者：
Altay B. [1 ]
KefI A. [1 ,2 ]
Tavmergen E. [1 ,2 ]
ÇIkIlI N. [1 ]
Semerci B. [1 ]
Goker E.T. [1 ,2 ]
机构：
[1] Ege University, Medical Faculty
[2] IVF Center, Ege University, Medical Faculty
来源：
International Urology and Nephrology | 2002年 / 33卷 / 1期
关键词：
Female age; Fertilization rate; Intracytoplasmic sperm injection (ICSI); Testicular sperm extraction (TESE);
D O I：
10.1023/A:1014425508427
中图分类号：
学科分类号：
摘要：
Introduction: Testicular sperm extraction (TESE) is well-defined procedure for surgical sperm retrieval in obstructive and non-obstructive azoospermia. This study was focused on the effectiveness of testicular sperm extraction and intracytoplasmic sperm injection (ICSI) for azoospermic men with different female age subgroups. Materials and methods: A total of 107 men with azoospermia underwent TESE and ICSI treatment. The women were examined in three groups 20-29, 30-34 and 35 years or older. The main outcome in this study was fertilization and pregnancy rates with TESE and ICSI. Results: Spermatozoa were successfully retrieved during 97 of 107 (90.7%) TESE attempts, resulting in the fertilization of 286 of 563 (50.4%) injected metaphase II oocytes. Two hundred and fifty-five of them were transferred (89.8%). The clinical pregnancy rate and ongoing pregnancy rate per embryo transfer were 22.5% and 20.6% respectively. When comparing the fertilization and pregnancy rates, it was observed that women between the ages of 20-29 years had significantly higher pregnancy rates than women over 34 years of age (p < 0.05). Conclusion: The female age is a major factor in determining successful implantation in ICSI.
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页码：95 / 99
页数：4
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