Methodology for quantiying absolute myocardial perfusion with PET and SPECT

被引：9
作者：
Lodge M.A. [1 ]
Bengel F.M. [1 ]
机构：
[1] Department of Radiology, The Johns Hopkins University, School of Medicine, Baltimore, MD 21287
来源：
Current Cardiology Reports | 2007年 / 9卷 / 2期
关键词：
Positron Emission Tomography; Myocardial Perfusion; Myocardial Blood Flow; Nuclear Cardiology; Coronary Flow Reserve;
D O I：
10.1007/BF02938338
中图分类号：
学科分类号：
摘要：
Noninvasive quantitative measurement of myocardial perfusion has played an important role in cardiac research and also has potential applications in clinical imaging. Positron emission tomography (PET) methods for measuring absolute perfusion are well established, although the need for an on-site cyclotron has restricted its use to a limited number of centers. Single-photon emission CT (SPECT) also has potential for quantifying myocardial perfusion and has more widespread availability. In this article we review the basic principles of absolute myocardial perfusion quantification and the radiopharmaceuticals that are available for both PET and SPECT. We also examine the extent to which recent developments in instrumentation have increased the practicality of absolute perfusion quantification in PET and the potential for absolute quantification in SPECT. Copyright © 2007 by Current Medicine Group LLC.
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收藏
页码：121 / 128
页数：7
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