Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression

Morris SW(1994)Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma Science 263 1281-1284

Kirstein MN(2009)Anaplastic lymphoma kinase: signalling in development and disease Biochemical Journal 420 345-361

Valentine MB(2005)Truncated ALK derived from chromosomal translocation t(2;5)(p23;q35) binds to the SH3 domain of p85-PI3K Mutation Research 570 9-15

Dittmer KG(2007)Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases American Journal of Surgical Pathology 31 509-520

Shapiro DN(2008)Oncogenic mutations of ALK kinase in neuroblastoma Nature 455 971-974

Saltman DL(2008)Activating mutations in ALK provide a therapeutic target in neuroblastoma Nature 455 975-978

Look AT(2008)Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.[see comment] Nature 455 967-970

Palmer RH(2007)Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.[see comment] Nature 448 561-566

Vernersson E(2004)Heterogeneity of genomic breakpoints in MSN-ALK translocations in anaplastic large cell lymphoma Human Pathology 35 1038-1041

Grabbe C(2007)A case of an inflammatory myofibroblastic tumor in the lung which expressed TPM3-ALK gene fusion Pediatric Surgery International 23 595-599

Morris SW(1994)Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma Science 263 1281-1284

Kirstein MN(2009)Anaplastic lymphoma kinase: signalling in development and disease Biochemical Journal 420 345-361

Valentine MB(2005)Truncated ALK derived from chromosomal translocation t(2;5)(p23;q35) binds to the SH3 domain of p85-PI3K Mutation Research 570 9-15

Dittmer KG(2007)Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases American Journal of Surgical Pathology 31 509-520

Shapiro DN(2008)Oncogenic mutations of ALK kinase in neuroblastoma Nature 455 971-974

Saltman DL(2008)Activating mutations in ALK provide a therapeutic target in neuroblastoma Nature 455 975-978

Look AT(2008)Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.[see comment] Nature 455 967-970

Palmer RH(2007)Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.[see comment] Nature 448 561-566

Vernersson E(2004)Heterogeneity of genomic breakpoints in MSN-ALK translocations in anaplastic large cell lymphoma Human Pathology 35 1038-1041

Grabbe C(2007)A case of an inflammatory myofibroblastic tumor in the lung which expressed TPM3-ALK gene fusion Pediatric Surgery International 23 595-599