Synthesis of spiro[pyrazoloquinoline-oxindoles] and spiro[chromenopyrazolo-oxindoles] promoted by guanidine-functionalized magnetic Fe3O4 nanoparticles

被引:0
作者
Fatemeh Alemi Tameh
Javad Safaei-Ghomi
机构
[1] Islamic Azad University,Department of Chemistry, Science and Research Branch
来源
Journal of the Iranian Chemical Society | 2018年 / 15卷
关键词
Fe; O; nanoparticles; Heterogeneous catalyst; Spirooxindoles; One pot reaction;
D O I
暂无
中图分类号
学科分类号
摘要
Magnetic nanoparticles (MNPs) Fe3O4-immobilized guanidine (Fe3O4 MNPs-guanidine) have been used as an efficient catalyst for the preparation of spiro[pyrazoloquinoline-oxindoles] and spiro[chromenopyrazolo-oxindoles] by four-component reactions of phenylhydrazine or hydrazine hydrate, isatins, ketoesters and naphthylamine or 2-naphthol under reflux condition in ethanol. This method provides several advantages including mild reaction conditions, the applicability to a wide range of substrates, the reusability of the catalyst and low catalyst loading.
引用
收藏
页码:1633 / 1637
页数:4
相关论文
共 90 条
  • [1] Kitajima M(2007)undefined J. Nat. Med. 61 14-undefined
  • [2] Pandey R(2006)undefined Phytochem 67 2164-undefined
  • [3] Singh SC(1996)undefined Helv. Chim. Acta 79 151-undefined
  • [4] Gupta MM(2012)undefined Eur. J. Med. Chem. 51 79-undefined
  • [5] Pellegrini C(2004)undefined Bioorg. Med. Chem. 12 2483-undefined
  • [6] Weher M(2013)undefined Mol. Divers. 17 271-undefined
  • [7] Borschberg H-J(2009)undefined Heterocycl. Commun. 15 355-undefined
  • [8] Bhaskar G(2009)undefined Eur. J. Med. Chem. 44 1257-undefined
  • [9] Arun Y(2009)undefined Eur. J. Med. Chem. 44 3272-undefined
  • [10] Balachandran C(2016)undefined Mol. Divers. 20 299-undefined