Sex-biased molecular differences in lung adenocarcinoma are ethnic and smoking specific

被引:0
作者
Xuetao Li
Shuquan Wei
Liaoyuan Deng
HongYan Tao
Mingkai Liu
Ziwen Zhao
Xin Du
Yujun Li
Jun Hou
机构
[1] Tongji Medical College,Department of Oncology, Maternal and Child Health Hospital of Hubei Province
[2] Huazhong University of Science and Technology,School of Medicine
[3] South China University of Technology,Department of Pulmonary and Critical Care Medicine
[4] Guangzhou First People’s Hospital,Department of Pulmonary Diseases
[5] School of Medicine,Department of Hematology, Guangdong Provincial People’s Hospital
[6] South China University of Technology,Center for Medical Research On Innovation and Translation
[7] The Second Affiliated Hospital of Lanzhou University,undefined
[8] Guangdong Academy of Medical Sciences,undefined
[9] Institute of Clinical Medicine,undefined
[10] Guangzhou First People’s Hospital,undefined
[11] School of Medicine,undefined
[12] South China University of Technology,undefined
来源
BMC Pulmonary Medicine | / 23卷
关键词
Sex differences; Genomic profiles; Tumor-infiltrating immune cells; Gene expression; Lung adenocarcinoma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 253 条
  • [1] Haupt S(2021)Sex disparities matter in cancer development and therapy Nat Rev Cancer 21 393-407
  • [2] Caramia F(2011)Contribution of smoking-related and alcohol-related deaths to the gender gap in mortality: evidence from 30 European countries Tob Control 20 166-168
  • [3] Klein SL(2018)Cancer immunotherapy efficacy and patients’ sex: a systematic review and meta-analysis Lancet Oncol 19 737-746
  • [4] Rubin JB(2019)Sex-based heterogeneity in response to lung cancer immunotherapy: a systematic review and meta-analysis J Natl Cancer Inst 111 772-781
  • [5] Haupt Y(2019)Sex differences in tolerability to anti-programmed cell death protein 1 therapy in patients with metastatic melanoma and non-small cell lung cancer: are we all equal? Oncologist 24 e1148-e1155
  • [6] McCartney G(2018)Sex Differences in cancer driver genes and biomarkers Cancer Res 78 5527-5537
  • [7] Mahmood L(2020)Sex differences in oncogenic mutational processes Nat Commun 11 4330-722
  • [8] Leyland AH(2016)Comprehensive characterization of molecular differences in cancer between male and female patients Cancer Cell 29 711-5768
  • [9] Batty GD(2016)Analysis of cancer genomes reveals basic features of human aging and its role in cancer development Nat Commun 7 12157-1182
  • [10] Hunt K(2007)The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non–small cell lung cancer Clin Cancer Res 13 5763-1134