Rapid detection of mutations in CSF-cfTNA with the Genexus Integrated Sequencer

被引:0
作者
Srividya Arjuna
Mauli Shah
Antonio Dono
Luis Nunez-Rubiano
Pavel S. Pichardo-Rojas
Jay-Jiguang Zhu
Roy F. Riascos
Rajyalakshmi Luthra
Sinchita Roy-Chowdhuri
Dzifa Duose
Daniel H. Wang
Frederick F. Lang
Yoshua Esquenazi
Leomar Y. Ballester
机构
[1] The University of Texas MD Anderson Cancer Center Houston,Department of Translational Molecular Pathology
[2] McGovern Medical School at UT Health,Vivian L. Smith Department of Neurosurgery
[3] McGovern Medical School at UT Health,Department of Diagnostic and Interventional Imaging
[4] Memorial Hermann Hospital-TMC,Department of Hematopathology
[5] The University of Texas MD Anderson Cancer Center at Houston,Department of Pathology
[6] The University of Texas MD Anderson Cancer Center Houston,Department of Neurosurgery
[7] The University of Texas MD Anderson Cancer Center Houston,Center for Precision Health, Vivian L. Smith Department of Neurosurgery
[8] The University of Texas Health Science Center at Houston,Neuropathology and Molecular Genetic Pathology, Department of Pathology
[9] The University of Texas MD Anderson Cancer Center Houston,undefined
来源
Journal of Neuro-Oncology | 2024年 / 166卷
关键词
CSF; ctDNA; cfDNA; Genexus; Liquid biopsy; Brain metastases; Lung cancer; Breast cancer; Cerebrospinal fluid;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:39 / 49
页数:10
相关论文
共 21 条
[1]  
Barnholtz-Sloan JS(2004)Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System J Clin Oncol 22 2865-2872
[2]  
Schouten LJ(2002)Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma Cancer 94 2698-2705
[3]  
Ali S(2021)Molecular profiles of brain metastases: a focus on heterogeneity Cancers 13 2645-88
[4]  
Heitzer E(2019)Current and future perspectives of liquid biopsies in genomics-driven oncology Nat Rev Genet 20 71-6
[5]  
De Mattos-Arruda L(2015)Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma Nat Commun 6 1-306
[6]  
Pan C(2019)Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA Acta Neuropathol 137 297-9709
[7]  
Wang Y(2015)Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord Proc Natl Acad Sci USA 112 9704-522
[8]  
Bettegowda C(2014)Detection of circulating tumor DNA in early- and late-stage human malignancies Sci Transl Med 6 24-6
[9]  
Pan W(2015)Brain tumor mutations detected in cerebral spinal fluid Clin Chem 61 514-270
[10]  
Takayasu T(2020)Cerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors Sci Rep 10 14326-2415