Alternative Splicing of Murine Interleukin-4 mRNA

被引：0
|
作者：
O. P. Yatsenko
M. L. Filipenko
E. N. Voronina
E. A. Khrapov
S. V. Sennikov
V. A. Kozlov
机构：
[1] Siberian Division of Russian Academy of Medical Sciences; Institute of Chemical Biology and Fundamental Medicine,Laboratory of Immunopoesis Regulation, Institute of Clinical Immunology
[2] Siberian Division of Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 137卷
关键词：
interleukin-4; alternative splicing;
D O I：
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学科分类号：
摘要：
We found an alternative form of mRNA with spliced second exon (IL-4δ2 mRNA) in mouse bone marrow and splenic cells. At rest, the amount of IL-4 mRNA markedly surpassed that of IL-4δ2 mRNA. Stimulation increased the content of both mRNA forms, but the alternative variant is accumulated more intensively and rapidly. We did not detect predominance of IL-4δ2 mRNA over full-lenght mRNA variant in the studied mouse tissues.
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页码：179 / 181
页数：2
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