T-cell receptor-α CDR3 domain chemical features correlate with survival rates in bladder cancer

被引:0
作者
Boris I. Chobrutskiy
Saif Zaman
Andrea Diviney
Moody M. Mihyu
George Blanck
机构
[1] University of South Florida,Department of Molecular Medicine, Morsani College of Medicine
[2] H. Lee Moffitt Cancer Center and Research Institute,Immunology Program
来源
Journal of Cancer Research and Clinical Oncology | 2019年 / 145卷
关键词
T-cell receptor-alpha CDR3; Biochemical features; Cancer survival outcomes; Bioinformatics; Antigen chemical complementarity;
D O I
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中图分类号
学科分类号
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页码:615 / 623
页数:8
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[1]  
Brown SD(2015)Profiling tissue-resident T cell repertoires by RNA sequencing Genome Med 7 125-223
[2]  
Raeburn LA(2018)T cell receptor-beta J usage, in combination with particular HLA class II alleles, correlates with better cancer survival rates Immunol Res 66 219-4388
[3]  
Holt RA(2000)Induction of antitumor immunity with combination of HER2/neu DNA vaccine and interleukin 2 gene-modified tumor vaccine Clin Cancer Res 6 4381-2045
[4]  
Callahan BM(2013)CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia PloS One 8 e61338-548
[5]  
Tong WL(2015)Collagen specific T-cell repertoire and HLA-DR alleles: biomarkers of active refractory rheumatoid arthritis EBioMedicine 2 2037-28
[6]  
Blanck G(1987)Local immune responses after intravesical BCG treatment for carcinoma in situ Br J Urol 60 543-549
[7]  
Chen SA(2016)Detection of productively rearranged TcR-alpha V-J sequences in TCGA exome files: implications for tumor immunoscoring and recovery of antitumor T-cells Cancer Inf 15 23-732
[8]  
Tsai MH(2015)Somatic variation of T-cell receptor genes strongly associate with HLA class restriction PloS One 10 e0140815-483
[9]  
Wu FT(2015)Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor J Clin Oncol 33 540-7404
[10]  
Hsiang A(2016)Landscape of tumor-infiltrating T cell repertoire of human cancers Nature genetics 48 725-6435