Innate recognition of non-self nucleic acids

被引：0
作者：
Hongbo Chi
Richard A Flavell
机构：
[1] St Jude Children's Research Hospital,Department of Immunology
[2] Yale University School of Medicine,Howard Hughes Medical Institute and Department of Immunobiology
来源：
Genome Biology | / 9卷
关键词：
West Nile Virus; Endosomal Compartment; Interferon Response; Japanese Encephalitis Virus; Innate Immune Receptor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The immune system has evolved a plethora of innate receptors that detect microbial DNA and RNA, including Toll-like receptors in the endosomal compartment and RIG-I-like receptors and Nod-like receptors in the cytosol. Here we discuss the recognition of and responses to non-self nucleic acids via these receptors as well as their involvement in autoimmune diseases.
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