Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus

[1] Pan HF(2013)Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients Rheumatol Int 33 2337-2342

[2] Wu GC(2011)Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus Mol Biol Rep 38 4077-4081

[3] Fan YG(2012)IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms J Immunol 189 1081-1093

[4] Leng RX(2009)A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice Proc Natl Acad Sci USA 106 1518-1523

[5] Peng H(2007)IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R. Fc reduces disease progression J Immunol 178 3822-3830

[6] Zhou M(2012)IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice J Immunol 188 1656-1667

[7] Li BZ(2005)Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus Int J Mol Med 16 609-615

[8] Zhu Y(2010)Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity J Clin Immunol 30 45-52

[9] Tao JH(2011)Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus Arthritis Res Ther 13 R157-1828

[10] Li XP(2012)Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus J Rheumatol 39 1819-179

[1] Pan HF(2013)Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients Rheumatol Int 33 2337-2342

[2] Wu GC(2011)Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus Mol Biol Rep 38 4077-4081

[3] Fan YG(2012)IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms J Immunol 189 1081-1093

[4] Leng RX(2009)A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice Proc Natl Acad Sci USA 106 1518-1523

[5] Peng H(2007)IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R. Fc reduces disease progression J Immunol 178 3822-3830

[6] Zhou M(2012)IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice J Immunol 188 1656-1667

[7] Li BZ(2005)Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus Int J Mol Med 16 609-615

[8] Zhu Y(2010)Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity J Clin Immunol 30 45-52

[9] Tao JH(2011)Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus Arthritis Res Ther 13 R157-1828

[10] Li XP(2012)Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus J Rheumatol 39 1819-179