Frequency of multiple primary cancers in the lung and other organs in hemodialysis patients

被引：3

作者：

Obuchi T. ^{[1
]}

Saito T. ^{[2
]}

Iwasaki A. ^{[3
]}

机构：

[1] Department of Thoracic Surgery, St. Mary's Hospital, Kurume 830-8543

[2] Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka

[3] Department of Thoracic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka

来源：

General Thoracic and Cardiovascular Surgery | 2012年 / 60卷 / 8期

关键词：

Hemodialysis; Long-term survival; Lung cancer; Multiple primary cancers; Surgery;

D O I：

10.1007/s11748-012-0085-4

中图分类号：

学科分类号：

摘要：

Objective: We examined whether cancers frequently occur in hemodialysis patients, and therefore, investigated the features and outcomes of hemodialysis patients who had undergone surgery for non-small cell lung cancer. Methods: Between 1995 and 2011, 14 hemodialysis patients with lung cancer (8 males and 6 females) with a mean age of 67.0 years successfully underwent pulmonary resection at our institution. We investigated the 5-year survival rate and causes of death. The occurrence of multiple primary cancers in our patients and other lung-cancer patients reported in the articles were statistically compared by Chi-square test. A p value <0.05 was considered to be statistically significant. Results: The 5-year survival rate was 47.3 %, and six patients had died before our investigation. Four of the six had died of non-cancerous diseases related to hemodialysis. Five of 14 patients had a history of other primary cancers in other organs, and this incidence rate of multiple primary cancers was significantly higher than in other lung-cancer patients (p = 0.0071). Conclusion: The frequency of cancer in hemodialysis patients can be underestimated because of their early deaths by non-cancerous diseases. However, the incidence rate of multiple primary cancers may represent a unique characteristic of such patients. © The Japanese Association for Thoracic Surgery 2012.

引用

页码：489 / 493

页数：4

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