Engrailed2 modulates cerebellar granule neuron precursor proliferation, differentiation and insulin-like growth factor 1 signaling during postnatal development

被引:0
作者
Ian T Rossman
Lulu Lin
Katherine M Morgan
Marissa DiGiovine
Elise K Van Buskirk
Silky Kamdar
James H Millonig
Emanuel DiCicco-Bloom
机构
[1] The State University of New Jersey,Department of Neuroscience & Cell Biology, Robert Wood Johnson Medical School, Rutgers
[2] The State University of New Jersey,Department of Pediatrics (Child Neurology & Neurodevelopmental Disabilities), Robert Wood Johnson Medical School, Rutgers
[3] Center for Pediatric Neurology & Neurosurgery,Department of Medicine, The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers
[4] Cleveland Clinic,Department of Neurology
[5] The State University of New Jersey,Department of Biology
[6] Children's Hospital of Philadelphia,Center for Advanced Biotechnology and Medicine, Rutgers
[7] Duke University,undefined
[8] The State University of New Jersey,undefined
[9] Piscataway,undefined
来源
Molecular Autism | / 5卷
关键词
Autism; IGF1; Cerebellum; Neurodevelopment; Cell cycle; Proliferation; Phospho-S6 kinase;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 512 条
[1]  
Davis CA(1988)Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain Genes Dev 2 361-371
[2]  
Noble-Topham SE(1996)Engrailed, Wnt and Pax genes regulate midbrain–hindbrain development Trends Genet 12 15-20
[3]  
Rossant J(2005)Neuroanatomic observations of the brain in autism: a review and future directions Int J Dev Neurosci 23 183-187
[4]  
Joyner AL(1997)An MRI study of autism: the cerebellum revisited Neurology 49 546-551
[5]  
Joyner AL(2009)A comprehensive volumetric analysis of the cerebellum in children and adolescents with autism spectrum disorder Autism Res 2 246-257
[6]  
Bauman ML(2012)Consensus paper: pathological role of the cerebellum in autism Cerebellum 11 777-807
[7]  
Kemper TL(2005)Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus Am J Hum Genet 77 851-868
[8]  
Piven J(2008)Heterogeneous association between Engrailed-2 and autism in the CPEA network Am J Med Genet B Neuropsychiatr Genet 147B 187-193
[9]  
Saliba K(2004)Association of the homeobox transcription factor, ENGRAILED 2, with autism spectrum disorder Mol Psychiatry 9 474-484
[10]  
Bailey J(2010)Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population Genes Brain Behav 9 248-255