5-hydroxymethylcytosine is highly dynamic across human fetal brain development

被引:0
作者
Helen Spiers
Eilis Hannon
Leonard C. Schalkwyk
Nicholas J. Bray
Jonathan Mill
机构
[1] University of Oxford,Department of Physics
[2] University of Exeter Medical School,School of Biological Sciences
[3] RILD Building,MRC Centre for Neuropsychiatric Genetics and Genomics
[4] Royal Devon and Exeter Hospital,undefined
[5] University of Essex,undefined
[6] Cardiff University School of Medicine,undefined
来源
BMC Genomics | / 18卷
关键词
Human Fetal Brain Development; Post-conception Day (DPC); Human Neurodevelopment; 5hmC Detection; Human Developmental Biology Resource (HDBR);
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  • [1] Vaquerizas JM(2009)A census of human transcription factors: function, expression and evolution Nat Rev Genet 10 252-263
  • [2] Kummerfeld SK(2013)Global epigenomic reconfiguration during mammalian brain development Science 341 1237905-352
  • [3] Teichmann SA(2015)Methylomic trajectories across human fetal brain development Genome Res 25 338-935
  • [4] Luscombe NM(2009)Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 Science 324 930-5605
  • [5] Lister R(2003)Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b Mol Cell Biol 23 5594-930
  • [6] Mukamel EA(2009)The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain Science 324 929-1043
  • [7] Nery JR(2012)5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary Nat Struct Mol Biol 19 1037-1159
  • [8] Urich M(2013)Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives Cell 152 1146-1510
  • [9] Puddifoot CA(2013)A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation Genome Biol 14 R119-1430
  • [10] Johnson ND(2010)Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine Nucleic Acids Res 38 e125-340