Effect of Pluronic F127 on the photosensitizing properties of dimegine in the presence of nanoparticles

被引：0
作者：
N. A. Aksenova
V. V. Kardumyan
N. N. Glagolev
V. T. Shashkova
I. A. Matveeva
P. S. Timashev
A. B. Solov’eva
机构：
[1] Russian Academy of Sciences,Semenov Institute of Chemical Physics
[2] Russian Academy of Sciences,Institute of Laser and Information Technologies
来源：
Russian Journal of Physical Chemistry A | 2015年 / 89卷
关键词：
porphyrin photosensitizers; nanoparticles; amphiphilic polymers; photooxidation of tryptophan; photodynamic therapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
It is shown that the activity of the water-soluble porphyrin photosensitizer dimegine (DMG) in the oxidation reaction of tryptophan, a test reaction for photodynamic therapy (PDT), can be enhanced by introducing silver, gold, and hydroxyapatite nanoparticles (NP) into the reaction medium if an amphiphilic polymer (AP) with the properties of a SAS is introduced into this mixture. It is concluded that the effect of enhancing the photosensitizing activity of dimegine is due to the formation of nanoparticle-Pluronic-porphyrin triple systems in which Pluronic (PL) plays the role of a bridge, forming complex and adsorption bonds with porphyrin and nanoparticles.
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页码：1486 / 1491
页数：5
相关论文
共 76 条
[1]  
Solov’eva A B(2011)undefined Ross. Bioterapevt. Zh. 10 81-undefined
[2]  
Tolstykh P I(2012)undefined Photochem. Photobiol. 88 496-undefined
[3]  
Sorokatyi A A(2013)undefined Photon. Lasers Med. 2 189-undefined
[4]  
Hamblin M R(2002)undefined Langmuir 18 2985-undefined
[5]  
Aksenova N A(2012)undefined J. Photochem. Photobiol. B 107 35-undefined
[6]  
Zhientaev T M(2012)undefined J. Taiwan Inst. Chem. Eng. 43 996-undefined
[7]  
Brilkina A A(2010)undefined Saudi Pharmaceut. J. 18 179-undefined
[8]  
Hone D C(2012)undefined Polyhedron 34 114-undefined
[9]  
Walker P S(2010)undefined Small 6 745-undefined
[10]  
Evans-Gowing R(2010)undefined J. Biotechnol. Suppl. 150 192-undefined
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