Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome

被引:0
作者
Jinshan Xing
Xin Luo
Keran Jia
Shuang Liu
Shaokun Chen
Gan Qiao
Chunxiang Zhang
Jingyan Yi
机构
[1] The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Department of Neurosurgery
[2] Southwest Medical University,Department of Pharmacology, School of Pharmacy, Nucleic Acid Medicine of Luzhou Key Laboratory
[3] Southwest Medical University,Nucleic Acid Medicine of Luzhou Key Laboratory, Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Preventi
[4] The Affiliated Hospital of Southwest Medical University,Department of Reproductive Medicine
[5] Southwest Medical University,Department of Morphological Laboratory, School of Basic Medical Sciences
[6] Southwest Medical University,Department of Medical Cell Biology and Genetics, School of Basic Medical Sciences, Nucleic Acid Medicine of Luzhou Key Laboratory, Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiologica
来源
Journal of Ovarian Research | / 16卷
关键词
PCOS; ASP; Network pharmacology; PRKCA;
D O I
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学科分类号
摘要
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  • [1] Berman HM(2000)The Protein Data Bank Nucleic Acids Res 28 235-242
  • [2] Westbrook J(2013)Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model Int J Oncol 43 394-404
  • [3] Feng Z(2019)Asparagus Polysaccharide Suppresses the Migration, Invasion, and Angiogenesis of Hepatocellular Carcinoma Cells Partly by Targeting the HIF-1α/VEGF Signalling Pathway In Vitro Evid Based Complement Alternat Med 2019 3769879-225
  • [4] Gilliland G(2015)DHEA, DHEAS and PCOS J Steroid Biochem Mol Biol 145 213-467
  • [5] Bhat TN(2019)MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN Reprod Biol Endocrinol 17 68-767
  • [6] Weissig H(2018)Ethnicity, obesity and the prevalence of impaired glucose tolerance and type 2 diabetes in PCOS: a systematic review and meta-regression Hum Reprod Update 24 455-133
  • [7] Bousserouel S(2002)New approach to polycystic ovary syndrome and other forms of anovulatory infertility Obstet Gynecol Surv 57 755-80
  • [8] Le Grandois J(2017)Aqueous root extract of Asparagus cochinchinensis (Lour.) Merr. Has antioxidant activity in D-galactose-induced aging mice BMC Complement Altern Med 17 469-422
  • [9] Gossé F(2021)Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling Pharmacol Res 171 38134-2504
  • [10] Werner D(2016)Impaired receptivity and decidualization in DHEA-induced PCOS mice Sci Rep 6 67-d613